Effect of Chewing Gum Containing Sodium Bicarbonate on Human Interproximal Plaque pH

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Abstract
The effect of chewing sorbitol gum containing sodium bicarbonate on interproximal plaque pH was determined by use of an ion-sensitive field-effect transistor (ISFET) electrode system with four human volunteers. Plaque pH was lowered by 2 min of chewing of a sucrose-containing toffee. After 20 min, either sodium bicarbonate or control gum was chewed for 10 min, and the pH was followed for an additional 20 min. The minimum pH after toffee chewing was elevated by both the control gum (4.5 ± 0.3 to 5.2 ± 0.5) and the sodium-bicarbonate-containing product (4.3 ± 0.3 to 6.1 ± 0.6) to levels which were significantly different (p