Sulfisoxazole as Chemoprophylaxis for Recurrent Otitis Media
- 26 September 1974
- journal article
- clinical trial
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 291 (13) , 664-667
- https://doi.org/10.1056/nejm197409262911307
Abstract
ACUTE otitis media is a common problem in pediatric practice. Its incidence in the first decade of life is usually reported to be 10 to 20 episodes per 100 children per year,1 , 2 with an even higher incidence in certain high-risk populations.3 , 4 The epidemiology of recurrent otitis media has not been extensively studied although the tendency to recurrences is marked, especially among younger children. Approximately half those with otitis during a one-year period will have had at least one previous attack.1 , 2 Prospectively, 20 per cent of patients with acute otitis will suffer at least one recurrence in three years.5 The main . . .Keywords
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