Sequence features of the replication terminus of theBacillus subtilischromosome
Open Access
- 1 January 1987
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 15 (20) , 8501-8509
- https://doi.org/10.1093/nar/15.20.8501
Abstract
The sequence of 1267 nucleotides spanning the replication terminus, terC, of the Bacillus subtils 1s168 chromosome has been determined. The site of arrest of the clockwise fork, which defines terC, has been localized to a 30-nucleotide portion (approximately) within this sequence. The arrest site occurs 1n an A+T-r1ch region between two open reading frames and very close to one of two imperfect inverted repeats (47–48 nucleotides each) which are separated by 59 nucleotides. The closeness of approach of the arrested clockwise fork to the first Imperfect Inverted repeat encountered in this region raises the possibility of a role for the Inverted repeats in the mechanism of fork arrest.Keywords
This publication has 7 references indexed in Scilit:
- Cloning and localization of the Bacillus subtilis chromosome replication terminus, terCGene, 1985
- Physical map of the Bacillus subtilis replication terminus region: its confirmation, extension and genetic orientationGene, 1984
- The role of palindromic and non-palindromic sequences in arresting DNA synthesis in vitro and in VivoJournal of Molecular Biology, 1984
- A unique DNA intermediate associated with termination of chromosome replication in Bacillus subtilisCell, 1984
- Restriction map of DNA spanning the replication terminus of the Bacillus subtilis chromosomeJournal of Molecular Biology, 1983
- The nucleotide sequence surrounding the replication terminus of R6K.Proceedings of the National Academy of Sciences, 1981
- DNA sequencing with chain-terminating inhibitorsProceedings of the National Academy of Sciences, 1977