Post-transfusion purpura secondary to passive transfer of anti-P1A1by blood transfusion
- 1 May 1987
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 66 (1) , 113-114
- https://doi.org/10.1111/j.1365-2141.1987.tb06899.x
Abstract
A patient developed severe post-transfusion purpura (PTP) following transfusion of two units of packed red blood cells. The timing of the patient''s thombocytopenia suggested passive immunization rather than the typical anamnestic response associated with classical PTP. Investigation of the blood donors revealed one with evidence of a platelet specific anibody of high titre. This donor was typed as P1A1 negative and the antibody was shown to have anti-P1A1 specificity.This publication has 3 references indexed in Scilit:
- Post‐transfusion purpura: A report of five patients and a review of the pathogenesis and managementAmerican Journal of Hematology, 1986
- A Simple Immunofluorescence Test for the Detection of Platelet AntibodiesBritish Journal of Haematology, 1978
- IMMUNOREACTIONS INVOLVING PLATELETS. V. POST-TRANSFUSION PURPURA DUE TO A COMPLEMENT-FIXING ANTIBODY AGAINST A GENETICALLY CONTROLLED PLATELET ANTIGEN. A PROPOSED MECHANISM FOR THROMBOCYTOPENIA AND ITS RELEVANCE IN “AUTOIMMUNITY”*Journal of Clinical Investigation, 1961