Antiretroviral therapy with tenofovir is associated with mild renal dysfunction
- 1 January 2005
- journal article
- research article
- Published by Wolters Kluwer Health in AIDS
- Vol. 19 (1) , 93-95
- https://doi.org/10.1097/00002030-200501030-00012
Abstract
A cross-sectional study was conducted to compare patients treated with tenofovir with patients never treated with tenofovir. Patients on tenofovir showed a lower mean glomerular filtration rate estimated by creatinine clearance or cystatin C clearance compared with control patients. In total, 24 patients on tenofovir versus five control patients had proteinuria greater than 130 mg/day. In the majority of patients on tenofovir proteinuria was of tubular origin.Keywords
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