Plasma C reactive protein concentration indicates a direct relation between systemic inflammation and social deprivation

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Abstract
Inflammation is important in the development of atherosclerosis, plaque rupture, and thrombosis leading to myocardial infarction. An increase in the plasma concentration of C reactive protein (CRP), within the reference range for the population but below the threshold that indicates clinically significant inflammation, is an independent risk factor for CHD.3 It is also a predictor for the development of diabetes mellitus4—a major cause of vascular disease. We have investigated the relation between the plasma CRP concentration and social deprivation in two large study populations.