CORNEAL MEMBRANE WATER PERMEABILITY AS A FUNCTION OF TEMPERATURE

  • 1 January 1976
    • journal article
    • research article
    • Vol. 15  (4) , 304-307
Abstract
Osmotically driven water flow across the [rabbit] corneal epithelium and endothelium was measured as a function of temperature. For both membranes deviations from a single straight-line relationship were found in a logarithmic plot of hydraulic conductivity against 1/T. Both membranes showed a high (14-16 kcal/mol) apparent activation energy at temperatures between 5.degree.-23.degree. C. At higher temperatures, between 23.degree.-37.degree. C, the apparent activation energy fell to 5.7 and 9.3 kcal/mol for the epithelium and endothelium, respectively. The low value for the apparent activation energy for water crossing the epithelium and endothelium at normal corneal temperatures presumably reflects water passage through water-filled channels.

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