Further Observations on the use of Combined Photic and Chemically Induced Cortical Dysrhythmia in Psychiatry

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Abstract
The work of Cossa and Gastaut (1) and Gastaut (2) indicated the possibility of inducing a cerebral dysrhythmia, consisting of fast spikes or a fast spike followed by a slow wave, by a method of combined metrazol and photic stimulation. Modifying their technique and substituting hexazol (triazol) for metrazol O'Flanaganet al.(3) treated a series of cases with encouraging results, and in view of their findings it was decided to investigate the method further, and examine the effect of the induced dysrhythmia with special reference to psychiatric disorders.