Prophylactic use of cephazolin against wound sepsis after cholecystectomy.
- 14 May 1977
- Vol. 1 (6071) , 1254-1256
- https://doi.org/10.1136/bmj.1.6071.1254
Abstract
A trial of antibiotic prophylaxis with cephazolin against postoperative wound sepsis was carried out on 201 patients undergoing routine cholecystectomy. Wound sepsis occurred in 11 out of 65 controls (16.9%), who were not given the drug; two out of 63 patients (3.2%) given a single dose preoperatively; and four out of 73 patients (5.5%) given the single preoperative dose plus a five-day course postoperatively. The difference between the controls and patients given the single preoperative dose was significant.Keywords
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