Glyceryl trinitrate is an effective treatment for anal fissure
- 1 April 1997
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Diseases of the Colon & Rectum
- Vol. 40 (4) , 468-470
- https://doi.org/10.1007/bf02258394
Abstract
PURPOSE:It has been suggested that chronic anal fissure is ischemic in origin because of poor blood supply and spasm of the internal anal sphincter. Nitric oxide donors such as glyceryl trinitrate (GTN) cause a chemical sphincterotomy leading to healing of the fissure. This study addresses tKeywords
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