Responsiveness of the Cerebral Circulation to Acute Alterations in Mean Arterial Pressure During the Administration of Propofol
- 1 December 1989
- journal article
- corsendonk workshop
- Published by Wolters Kluwer Health in Journal of Neurosurgical Anesthesiology
- Vol. 1 (4) , 375-376
- https://doi.org/10.1097/00008506-198912000-00015
Abstract
The responsiveness of the cerebral circulation to acute increases in mean arterial pressure was studied before and during the administration of propofol 3, 6, or 12 mg/kg/h in the anaesthetised baboon. Although mean arterial pressure increased significantly on each occasion, there were no significant changes in cerebral blood flow. This indicates that the physiological responsiveness of the cerebral circulation to alterations in mean arterial pressure was preserved during the administration of propofol in the concentrations studied.Keywords
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