Cyclization of 4-Hydroxy-(E)-2-alkenoic Esters: Simple Synthesis of Butenolides
- 1 January 1986
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1986 (05) , 416-417
- https://doi.org/10.1055/s-1986-31659
Abstract
Simple treatment of 4-hydroxy-(E)-2-alkenoic esters with benzenethiol leads to cyclization to give 3-phenylthio-4-alkanolides, which are easily converted into 3-phenylthio-2-alken-4-olides and 2-alken-4-olides (Δα,β-butenolides).Keywords
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