The Leader Sequence from the 5′-Terminus to the A-Protein Initiation Codon in MS2-Virus RNA
- 1 March 1971
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 68 (3) , 585-589
- https://doi.org/10.1073/pnas.68.3.585
Abstract
RNA fragments of different chain length, each containing the 5′-terminal guanosine tetraphosphate (pppGp) of bacteriophage-MS2 RNA, have been isolated from partial ribonuclease digests of the viral RNA. The longest fragment overlaps with the ribosomalbinding site of the A-protein cistron. The base sequence has been established for the major part. The results directly confirm that the A-protein cistron is closest to the 5′-terminus. Its initiating (AUG) codon starts at position 130, being preceded by an untranslated sequence of 129 nucleotides.Keywords
This publication has 12 references indexed in Scilit:
- Untranslated Nucleotide Sequence at the 5′-End of R 17 Bacteriophage RNANature, 1970
- Gene Order of RNA Bacteriophage M12Nature, 1970
- Gene Order in the Bacteriophage R17 RNA : 5′–;A Protein–Coat Protein–Synthetase–3′Nature, 1970
- Nucleotide Sequence from the Polypeptide Chain Termination Region of the Coat Protein Cistron in Bacteriophage R17 RNANature, 1970
- Polypeptide Chain Initiation: Nucleotide Sequences of the Three Ribosomal Binding Sites in Bacteriophage R17 RNANature, 1969
- Nucleotide Sequence from the Coat Protein Cistron of R17 Bacteriophage RNANature, 1969
- Studies on the bacteriophage MS2. V. The 5′‐terminal tetranucleotide sequence of the viral RNA chainFEBS Letters, 1968
- Limited enzymatic degradation of bacteriophage MS2 RNA.1968
- The Specific Cleavage of Yeast Ribosomal Ribonucleic Acid with Nucleases*Biochemistry, 1966
- Studies on the bacteriophage MS2Journal of Molecular Biology, 1965