Ciprofloxacin does not inhibit mitochondrial functions but other antibiotics do
Open Access
- 1 January 1990
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 34 (1) , 167-169
- https://doi.org/10.1128/aac.34.1.167
Abstract
At clinical concentrations, ciprofloxacin did not inhibit mitochondrial DNA replication, oxidative phosphorylation, protein synthesis, or mitochondrial mass (transmembrane potential). No difference in supercoiled forms of DNA was observed. The tetracyclines and chloramphenicol inhibited protein synthesis at clinically achievable concentrations, while rifampin, fusidic acid, and clindamycin did not.This publication has 30 references indexed in Scilit:
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