Cyclothialidine, a novel DNA gyrase inhibitor. I. Screening, taxonomy, fermentation and biological activity.

1 January 1994

journal article
Published by Japan Antibiotics Research Association in The Journal of Antibiotics

Vol. 47 (1) , 32-36
https://doi.org/10.7164/antibiotics.47.32

Abstract

Streptomyces filipinensis NR 0484 produced a new DNA gyrase inhibitor, cyclothialidine^1-3). It showed potent activity against DNA gyrases from Escherichia coli and Micrococcus luteus.

Keywords

STREPTOMYCES
DNA GYRASE
COLI
NOVEL DNA
LUTEUS
FILIPINENSIS
CYCLOTHIALIDINE1