Multiple Trichogenic Adnexal Tumors

Abstract
A young girl developed multiple generalized subcutaneous nodules and two polypoid ear lesions between birth and 8 years of age. There was no family history or evidence of systemic disease. The subcutaneous nodules were trichogenic myxomas, consisting of vascular myxoid connective tissue, sometimes with islands of stratified squamous epithelium, keratinous cysts of epidermal type, or dermoid cysts with follicular and/or sebaceous differentiation. The polypoid lesions were trichofolliculomas, with areas similar to trichogenic myxomas. Our patient thus has multiple trichogenic tumors, the majority being pure hamartomas of the dermal papilla (trichogenic myxomas), others being a combined trichogenic myxoma and hamartoma of hair germ (trichofolliculoma).

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