Preparation of 1-(Benzyloxycarbonyl) Hexahydro-3-Pyridazine Carboxylic Acid, A Protected Piperazic Acid
- 1 December 1988
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 18 (18) , 2225-2231
- https://doi.org/10.1080/00397918808082364
Abstract
A preparation of l-(benzyloxycarbonyl)hexahydro 3-pyridazinecarboxylic acid in five steps (73% overall yield) from 4-phenylurazole is described.Keywords
This publication has 6 references indexed in Scilit:
- The design and synthesis of the Angiotensin Converting Enzyme inhibitor Cilazapril and related bicyclic compoundsJournal of the Chemical Society, Perkin Transactions 1, 1986
- Hydrazinolysis of Urazoles: A Convenient and Mild Method for the Preparation of AzoalkanesSynthesis, 1981
- Piperazic acid and related compounds as inhibitors of GABA uptake in rat brain slicesJournal of Pharmacy and Pharmacology, 1977
- 4-PHENYL-1,2,4-TRIAZOLINE-3,5-DIONEOrganic Syntheses, 1971
- The Synthesis of Nitrogen-Containing Steroids. I. Diels-Alder Adducts of Steroids and 4-Phenyl-1,2,4-triazoline-3,5-dione1The Journal of Organic Chemistry, 1966
- The total synthesis of reserpineTetrahedron, 1958