Ocular Effects of Holmium (2.06 μM) and Erbium (1.54 μM) Laser Radiation

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Abstract
Ocular dose-response relationships were experimentally determined for selected exposure conditions at the erbium and holmium laser wavelengths of 1.54 and 2.06 .mu.m. The ocular responses were observed in Rhesus monkey eyes and were confined to the cornea. The ED50 (effective dose for 0.5 probability of producing a biomicroscopically visible corneal lesion) were determined for single corneal exposures. The depth and diameter of the corneal lesions were both dose and wavelength dependent. The wavelength dependence of the dose required to produce a corneal response is indicative of the relative absortion properties of the cornea. Current permissible exposure limits can be altered to reflect the relative absorption properties of the ocular media.

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