"In vitro" activity of gentian violet against asexual Plasmodium falciparum parasites

Open Access

1 February 1988

journal article
research article
Published by FapUNIFESP (SciELO) in Revista do Instituto de Medicina Tropical de São Paulo

Vol. 30 (1) , 17-20
https://doi.org/10.1590/s0036-46651988000100003

Abstract

In order to investigate whether gentian violet exhibited "in vitro" inhibitory activity against Plasmodium falciparum, the Authors have carried out 20 sensitivity tests according to the microtechnique described by RIECK MANN et al.5. Results have shown inhibition of schizonts'maturation at the following concentration: 1/1000; 1/1500; 1/2000; 1/2500; 1/3000 and 1/4000, thus demonstrating inhibitory activity of the tested dye against asexual blood parasites. The present data suggest gentain violet may be possibly used in the prophylaxis of transfusion-acquired malaria.

Keywords

This publication has 4 references indexed in Scilit:

Transfusion Malaria in the United States, 1972-1981
Annals of Internal Medicine, 1983
DRUG SENSITIVITY OF PLASMODIUM FALCIPARUM
The Lancet, 1978
Human Malaria Parasites in Continuous Culture
Science, 1976