OVARIAN GERMINOMAS (DYSGERMINOMAS)

  • 1 January 1978
    • journal article
    • research article
    • Vol. 51  (2) , 221-224
Abstract
The clinicopathologic findings of 13 patients with ovarian pure germinomas (dysgerminomas) were studied to assess modes of therapy. The patients'' ages ranged from 12-40 yr. Ten patients had unilateral tumors clinically confined to the ovary (stage I), including 1 patient who had an unsuspected microscopic germinoma in a normal-appearing ovary. Of those with stage I tumors, only 1 patient developed metastases and died. The presence of other elements in the metastases suggested that her primary ovarian neoplasm actually may have been a malignant mixed germ cell tumor. The other 9 patients are alive without tumor after postoperative intervals of 0.3-29 yr. Three patients had more advanced lesions (stages II-IV) and 2 died of metastases following orthovoltage irradiation. The results of this study support the concept of individualized therapy for patients with ovarian germinomas.

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