The identification of depsipeptides by chemical ionisation mass spectroscopy.
- 1 January 1979
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 32 (6) , 569-574
- https://doi.org/10.7164/antibiotics.32.569
Abstract
The chemical ionization mass spectra of 7 naturally occurring [antibiotic] depsipeptides and some of their permethylated derivatives were measured. The primary ionization process involves an ester group and not an amide or other functionality. It probably occurs randomly when the molecule contains more than 1 ester link. Unlike electron impact mass spectra, those obtained under chemical ionization conditions gave sequence information for all of the depsipeptides examined or their permethylated derivatives. A mechanism for the primary fragmentation is proposed.This publication has 0 references indexed in Scilit: