Long-Term Treatment of Trichotillomania (Hair Pulling)

Abstract
In 1989 we reported that clomipramine was superior to desipramine in reducing hair-pulling symptoms in trichotillomania1. Three of the 13 subjects completing the initial double-blind crossover trial had complete remissions during the five weeks of clomipramine treatment, and 9 had at least a 50 percent reduction in the severity of symptoms. These benefits were maintained for six months. The chronicity of the disorder and reports of relapses after prolonged drug treatment1-3 raised the question of long-term outcome.

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