The origin and destiny of cholesterol the animal organism. Part III.— The absorption of cholesterol from the food and its appearance in the blood

Abstract
In his 'Text-Book of Physiology’ Schäfer has suggested that the constant presence of lecithin and cholesterol in the bile may well be associated with the destruction of the red blood corpuscles which contain relatively large amounts of these substances, the latter, according to Hepner, being present in the free state and not in the form of esters. This idea has recently received strong support from the investigations of Chasoburd Kosumoto on the influence of toluylene diamine on the output of cholesterol in the bile. This reagent was found by Schmiedeberg to produce icterus, and Stadelmann, working in Schmiedeberg’s laboratory, observed that at the beginning of the action of the drug an increased production of bile took place. This, however, was only temporary, and soon the normal physical properties of the Idle underwent an alteration ; it became sticky, darker, and more concentrated.

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