Effect of X-Irradiation on Distribution and Properties of Cytoplasmic Particulates of Rat Liver

Abstract
On the basis of distribution of enzyme activities, there was no effect of 1000 r of total-body X-irradiation on the size distribution of mitochondria, lysosomes, or uricase particles of rat liver. There was also no effect of total body X-irradiation on spontaneous swelling or phos-phorylative capacity of rat liver mitochondria. It is concluded that the effects of radiation on rat liver mitochondria in vivo must be very slight. (This work was performed under the auspices of the U. S. Atomic Energy Commission.).