Chryscandin, a novel peptidyl nucleoside antibiotic. I Taxonomy, fermentation, isolation and characterization.
- 1 January 1984
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 37 (11) , 1279-1283
- https://doi.org/10.7164/antibiotics.37.1279
Abstract
A novel antifungal antibiotic, chryscandin was found in the culture broth of a strain of fungi. The producing organism was subsequently identified as Chrysosporium pannorum. The antibiotic obtained as colorless needle crystals (C20H23N7O6, MW 457) is active against Candida albicans and Gram-positive bacteria [Staphylococcus aureus], but it is ineffective against filamentous fungi and Gram-negative bacteria. Acute toxicity is very low in mice.This publication has 0 references indexed in Scilit: