Some Characteristics of Collagenase Activity in Gingival Crevicular Fluid and Its Relationship to Gingival Diseases in Humans
- 1 November 1976
- journal article
- other
- Published by SAGE Publications in Journal of Dental Research
- Vol. 55 (6) , 1049-1057
- https://doi.org/10.1177/00220345760550060701
Abstract
Collagenase activity in human gingival fluid was measured using a radioactive collagen fibril assay. The activity was positively correlated with the severity of gingival disease. The fluid collagenase seemed to be controlled by α2-macroglobulin, based on its activation by NaSCN, and to be present solely in the extracellular fraction. Examination of the collagen breakdown products by acrylamide gel electrophoresis indicated that the fluid collagenase was of tissue rather than bacterial origin.This publication has 30 references indexed in Scilit:
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