Variations in Blood Volume at 1.85 Km Altitude

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Abstract
In order to investigate further hematological variations at mid-altitude, plasma vol. (by means of the colloidal Geigy-blue dye), total cell vol., and hemoglobin concn. of 7 exptl. subjects (21-29 yr. of age) were detd. before, twice during, and after a 10-day sojourn at Uludag (1850 m.). From the values for plasma vol. and percentage plasma amt., total blood vol. was calculated. The plasma vol. remained practically unchanged during the period at mid-altitude, but was increased to 6.9% over the initial value 9-10 days after descent to sea level. Total blood vol. had increased 7.5% by the end of the 10-day period at mid-altitude. Although the total blood vol., 9-10 days after the return to sea level, was decreased when compared with the final mid-altitude value, it was still greater than the pre-expedition value. This relatively high blood vol. resulted chiefly from the increase in plasma vol., since the total cell vol. was practically normal. By the end of the 10-day period at mid-altitude, the total amt. of hemoglobin was 10.2% above the pre-expedition values, and total cell vol. was elevated 17.8%. On return to sea level, the hemoglobin remained at mid-altitude values while the cell vol. decreased.

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