Decreased Sensitivity to Insulin in White Adipose Tissue from Adrenalectomised Rats
- 1 January 1977
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 9 (06) , 474-480
- https://doi.org/10.1055/s-0028-1093503
Abstract
The ability of insulin to increase both [14C|-glucose incorporation into fatty acids and pyruvate dehydrogenasea activity in incubated rat epididymal adipose tissues was considerably lessened after adrenalectomy. Insulin antagonism of adrenaline-stimulated lipolysis in isolated fat cells was abolished after adrenalectomy. Percentage stimulation of lipolysis above basal by adrenaline was not appreciably altered by adrenalectomy.Keywords
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