Etomidate
- 1 March 1976
- journal article
- Published by Wolters Kluwer Health in Anesthesia & Analgesia
- Vol. 55 (2) , 286???289-9
- https://doi.org/10.1213/00000539-197603000-00035
Abstract
Clinical evaluation of etomidate, an ultrashortacting nonbarbiturate hypnotic agent, shows it to be useful for anesthetic induction in adults. It produces sleep in 1 arm-brain circulation time, metabolites apparently peaking at 7 minutes postinjection. Cardiovascular and respiratory systems appear minimally affected and there is no indication of organ toxicity or other biochemical or hematologic drug-induced disturbances. Moderate pain on injection at some sites and transient myoclonia were the principal disadvantages observed.Keywords
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