Iron, Anemia, and Infection
- 27 April 2009
- journal article
- review article
- Published by Oxford University Press (OUP) in Nutrition Reviews
- Vol. 55 (4) , 111-124
- https://doi.org/10.1111/j.1753-4887.1997.tb06462.x
Abstract
The data on the relationship between iron deficiency and infection are conflicting. Some researchers conclude that mild iron deficiency is beneficial for immunity, whereas others contend that any deficit is not good for immunity. Additionally, infection or inflammation generate anemia and profound changes in iron metabolism mediated by cytokines. These changes are important confounders to consider in assessments of iron status.Keywords
This publication has 61 references indexed in Scilit:
- The clinical significance of serum transferrin receptor levels in sickle cell diseaseBritish Journal of Haematology, 1993
- Monokines inhibiting erythropoietin production in human hepatoma cultures and in isolated perfused rat kidneysLife Sciences, 1992
- Erythropoietin Treatment of Anemia Associated with Multiple MyelomaNew England Journal of Medicine, 1990
- Consequences of starting whole cow milk at 6 months of ageThe Journal of Pediatrics, 1987
- Iron deficiency in infants: The influence of mild antecedent infectionThe Journal of Pediatrics, 1984
- Ribonucleotide Reductase—a Radical EnzymeScience, 1983
- Continual presence of oxygen and iron required for mammalian ribonucleotide reduction: Possible regulation mechanismBiochemical and Biophysical Research Communications, 1983
- Impaired immunocompetence associated with iron deficiencyThe Journal of Pediatrics, 1975
- The immune response in iron-deficient children: Impaired cellular defense mechanisms with altered humoral componentsThe Journal of Pediatrics, 1975
- The Effects of Francisella Tularensis Infection on Iron Metabolism in ManThe Lancet Healthy Longevity, 1969