The assay of pseudoephedrine hydrochloride in tablets and liquid formulations by two phase acid-base titration
- 1 September 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 32 (1) , 820-822
- https://doi.org/10.1111/j.2042-7158.1980.tb13083.x
Abstract
A novel titration method for the assay of pseudoephedrine hydrochloride in formulations is presented. Pseudoephedrine base is extracted into chloroform and titrated with acid in a two phase system. The method is specific for the drug in tablet and syrup formulations. The precision and speed of assay are comparable with existing spectrometric and titration methods for amine drugs.This publication has 4 references indexed in Scilit:
- Photometric acid-base titrations in the presence of an immiscible solventAnalytical Chemistry, 1979
- Investigation and automation of the fluorometric ion pair method for the determination of several amines in low dosage pharmaceuticalsAnalytical and Bioanalytical Chemistry, 1978
- Analysis of Binary Mixtures of Pharmaceutical Amines by the Acid Dye TechniqueJournal of Pharmaceutical Sciences, 1971
- Volumetric Determination of Quaternary Ammonium Compounds and Certain Tertiary AminesJournal of the American Pharmaceutical Association (Scientific ed.), 1954