Synthesis and characterization of the biological activity of the cisplatin analogs, cis-PtCl2(dexrazoxane) and cis-PtCl2(levrazoxane), of the topoisomerase II inhibitors dexrazoxane (ICRF-187) and levrazoxane (ICRF-186)
- 5 March 2004
- journal article
- Published by Elsevier in Journal of Inorganic Biochemistry
- Vol. 98 (4) , 616-624
- https://doi.org/10.1016/j.jinorgbio.2004.01.008
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Topoisomerase II Poisoning by ICRF-193Journal of Biological Chemistry, 2001
- Reactions of N,N′-dicarboxamido-N,N′-dicarboxymethyl-1,2-diaminoethane (EDTA–diamide) with hydrated ruthenium(III) chloride and potassium tetrachloroplatinate(II). Crystal and molecular structures of the pentadentate EDTA–H complex NH4[Ru(EDTA–H)Cl] · 2H2O and the EDTA–imide complex PtCl2[2(HOOCCH2)NCH2CH2NCH2CONHCOCH2] · 2H2OPolyhedron, 1998
- The preparation and crystal and molecular structure of the complex cis-PtCl2(razoxane)Inorganica Chimica Acta, 1998
- [20] Processing of X-ray diffraction data collected in oscillation modePublished by Elsevier ,1997
- Improved understanding in platinium antitumour chemistryChemical Communications, 1996
- An empirical correction for absorption anisotropyActa Crystallographica Section A Foundations of Crystallography, 1995
- An HPLC and spectrophotometric study of the hydrolysis of ICRF-187 (dexrazoxane, (+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane) and its one-ring opened intermediatesInternational Journal of Pharmaceutics, 1994
- The one-ring open hydrolysis product intermediates of the cardioprotective agent ICRF-187 (dexrazoxane) displace iron from iron-anthracycline complexesInflammation Research, 1993
- When good enzymes go bad: Conversion of topoisomerase II to a cellular toxin by antineoplastic drugsChemical Research in Toxicology, 1993
- Antitumour Activity in a Series of bisDiketopiperazinesNature, 1969