Immunization by the Intestinal Route of C3H-Mice against C3H-L-Ascites Tumor Cells

Abstract
Lumenal intracecal inoculation of viable malignant cells produces a protective effect against a secondary i.p. challenge with the same tumor cell. Cells inoculated in the lumen of the cecum showed immunizing properties as demonstrated by specific antibodies evidenced by a positive indirect immunofluorescence test. The protective effect can be transferred to an untreated animal by sensitized splenocytes.

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