Involvement of p21 in the PKC‐induced regulation of the G2/M cell cycle transition
Open Access
- 5 February 1999
- journal article
- Published by Wiley in FEBS Letters
- Vol. 444 (1) , 32-37
- https://doi.org/10.1016/s0014-5793(99)00022-8
Abstract
Activation of protein kinase C (PKC) inhibits cell cycle progression at the G1/S and G2/M transitions. We found that phorbol 12‐myristate 13‐acetate (PMA) induced upregulation of p21, not only in MCF...Keywords
This publication has 33 references indexed in Scilit:
- Cell cycle arrest and DNA endoreduplication following p21Waf1/Cip1 expressionOncogene, 1998
- Expression of a novel form of p21Cip1/Waf1 in UV-irradiated and transformed cellsOncogene, 1998
- Role of cdc25-C phosphatase in the immediate G2 delay induced by the exogenous factors epidermal growth factor and phorbolesterJournal of Cellular Physiology, 1996
- βII Protein Kinase C Is Required for the G2/M Phase Transition of Cell CyclePublished by Elsevier ,1996
- Inhibition of the Melanoma Cell Cycle and Regulation at the G1/S Transition by 12-O-Tetradecanoylphorbol-13-acetate (TPA) by Modulation of CDK2 ActivityExperimental Cell Research, 1995
- Phorbol Ester TPA Rapidly Prevents Activation of p34cdc2 Histone H1 Kinase and Concomitantly the Transition from G2 Phase to Mitosis in Synchronized HeLa CellsExperimental Cell Research, 1994
- The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNANature, 1994
- E2F1, B-MYB and Selective Members of Cyclin/CDK Subunits Are Targets for Protein Kinase C-Mediated Bimodal Growth Regulation in Vascular Endothelial CellsBiochemical and Biophysical Research Communications, 1994
- p21 is a universal inhibitor of cyclin kinasesNature, 1993
- WAF1, a potential mediator of p53 tumor suppressionCell, 1993