Gastro-Intestinal Microbleeding under Acetylsalicylic Acid, Ketoprofen and Placebo
- 1 January 1976
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in Rheumatology
- Vol. 15 (5) , 87-93
- https://doi.org/10.1093/rheumatology/15.5.87
Abstract
A quantitative comparison of gastro-intestinal microbleeding induced by acetylsalicylic acid (ASA), 3.6 g daily, ketoprofen (KETO), 200 mg daily and placebo (P) was undertaken in 12 normal volunteers using a double-blind factorial design with repeated measures. We conclude that KETO induces less gastro-intestinal bleeding than ASA but more than placebo and that there is a significant residual bleeding under placebo following ASA.Keywords
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