DEMONSTRATION OF VIRAL INCLUSION BODIES IN UNSTAINED TISSUE SECTIONS WITH THE AID OF THE PHASE MICROSCOPE I

Abstract
By means of bright-contrast, phase microscopy viral bodies were easily detected in unstained sections of tissues from yellow fever herpes simplex, fowl pox and distemper cases. The marked contrast and structural details shown by the inclusion bodies helped in their identification. The phase microscope offers promise for studies on the structure of inclusion bodies as well as in the diagnosis of viral diseases. Councilman bodies were observed in the liver of a child suffering a generalized herpes infection.