Glucuronidation of 7-Ethyl-10-hydroxycamptothecin (SN-38) by the Human UDP-Glucuronosyltransferases Encoded at the UGT1 Locus
- 24 June 1999
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 260 (1) , 199-202
- https://doi.org/10.1006/bbrc.1999.0453
Abstract
No abstract availableKeywords
This publication has 4 references indexed in Scilit:
- Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.Journal of Clinical Investigation, 1998
- Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implicationsPharmacogenetics, 1997
- Evidence for Overlapping Active Sites for 17α-Ethynlestradiol and Bilirubin in the Human Major Bilirubin UDPglucuronosyltransferaseBiochemistry, 1996
- Relationship between Development of Diarrhea and the Concentration of SN‐38, an Active Metabolite of CPT‐11, in the Intestine and the Blood Plasma of Athymic Mice Following Intraperitoneal Administration of CPT‐11Japanese Journal of Cancer Research, 1993