Plasma Phospholipide Deposition and Aortic Phospholipide Synthesis in Experimental Atherosclerosis

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Abstract
Rabbits on high cholesterol diets and normal controls were injected with H2P32O4 and with P32-labeled plasma lipoproteins to measure aortic phospholipid synthesis and plasma phospholipid deposition, respectively. Apparently the great majority of the phospholipid in the aortic plaque is not derived from circulating phospholipid but is synthesized in situ.