MINOR GRAFT-VERSUS-HOST REACTION - VERY EARLY EFFECTS ON HEPATIC AND EXOCRINE PANCREATIC FUNCTIONS IN MICE
- 1 January 1985
- journal article
- research article
- Vol. 39 (5) , 226-232
Abstract
The alterations of aspartate aminotransferase (GOT), lipase, .alpha.-amylase, glucose, urea and bilirubin plasma levels, as well as body weight and electrocardiogram tracings were monitored in individual mice, as organ dysfunction tests, throughout a graft-versus-host reaction (GVHR) induced by minor non-H-2 histocompatibility antigens. Starting in the first two weeks, elevations of GOT and decreases of .alpha.-amylase and lipase were found indicating deterioration of liver and exocrine pancreatic function.This publication has 3 references indexed in Scilit:
- Predictive Factors in Chronic Graft-Versus-Host Disease in Patients with Aplastic Anemia Treated by Marrow Transplantation from HLA-Identical SiblingsAnnals of Internal Medicine, 1983
- Ultrastructural lesions of bile ducts in primary biliary cirrhosisHuman Pathology, 1981
- Veno-Occlusive Disease of the Liver After Allogeneic Bone Marrow TransplantationAnnals of Internal Medicine, 1979