A Substrate-Phage Approach for Investigating Caspase Specificity
- 1 August 2004
- journal article
- Published by Springer Nature in Protein Journal
- Vol. 23 (6) , 413-425
- https://doi.org/10.1023/b:jopc.0000039555.92058.51
Abstract
We have developed a substrate-phage approach for examining the substrate specificities of an important group of proteases involved in apoptosis—the caspases. After establishing selection conditions...Keywords
This publication has 33 references indexed in Scilit:
- On the size of the active site in proteases. I. PapainPublished by Elsevier ,2005
- Polypyrimidine Tract-binding Proteins Are Cleaved by Caspase-3 during ApoptosisPublished by Elsevier ,2002
- Identification of Paracaspases and Metacaspases Two Ancient Families of Caspase-like Proteins, One of which Plays a Key Role in MALT LymphomaMolecular Cell, 2000
- Apoptotic Cleavage of Scaffold Attachment Factor A (SAF-A) by Caspase-3 Occurs at a Noncanonical Cleavage SitePublished by Elsevier ,2000
- Purification and catalytic properties of human caspase family membersCell Death & Differentiation, 1999
- Caspase-mediated Cleavage of DNA Topoisomerase I at Unconventional Sites during ApoptosisJournal of Biological Chemistry, 1999
- Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosisNature, 1995
- A survey of furin substrate specificity using substrate phage displayProtein Science, 1994
- Affinity Maturation of Human Growth Hormone by Monovalent Phage DisplayJournal of Molecular Biology, 1993
- Endonuclease activation during apoptosis: The role of cytosolic Ca2+ and pHBiochemical and Biophysical Research Communications, 1992