Increased efflux rather than oxidation is the mechanism of glutathione depletion by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

This publication has 15 references indexed in Scilit:

• Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase
  Published by Elsevier ,2004
• VI. Studies on the mechanism of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine cytotoxicity in isolated hepatocytes
  Life Sciences, 1987
• Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes
  Chemico-Biological Interactions, 1987
• Effect of 1-methyl-4-phemyl-1,2,3,6-tetrahydropyridine (MPTP) on levels of glutathione in the extrapyramidal system of the mouse
  Neuropharmacology, 1986
• Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients
  Neuroscience Letters, 1986
• Comparative studies on the mechanisms of paraquat and 1-methyl-4-phenylpyridine (MPP+) cytotoxicity
  Biochemical and Biophysical Research Communications, 1986
• 1-methyl-4-phenylpyridine (MPP+) induces oxidative stress in the rodent
  Life Sciences, 1986
• Dopaminergic toxicity after the stereotaxic administration of the 1-methyl-4-phenylpyridinium ion (MPP+) to rats
  Neuroscience Letters, 1985
• Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism
  Nature, 1984
• [4] Isolation and use of liver cells
  Published by Elsevier ,1978