Mapping of the α-1,6-fucosyltransferase gene, FUT8, to human chromosome 14q24.3
- 7 May 1999
- journal article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 84 (1-2) , 58-60
- https://doi.org/10.1159/000015215
Abstract
α-1,6-Fucosyltransferase (α1,6FucT) is involved in the biosynthesis of asparagine-linked glycoprotein oligosaccharides. In this study, we isolated a genomic clone for the human α1,6FucT gene (FUT8) and mapped it by fluorescence in situ hybridization to chromosome 14q24.3. This study suggests a distinct localization of FUT8 from genes for other human fucosyltransferases reported to date.Keywords
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