Immunocytochemical localization of rat peripheral nervous system myelin proteins: P2 protein is not a component of all peripheral nervous system myelin sheaths.

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Abstract
Specific antibodies were developed against P1, P2 and PO myelin proteins and were used to study the localization of these proteins in the rat peripheral nervous system. Both peripheral and CNS myelin sheaths contain P0 protein. P0 and P2 proteins are found exclusively in peripheral nervous system myelin sheaths. Antisera to P1 and P0 proteins stain all peripheral nervous system myelin sheaths uniformly. P2 protein is not a component of all peripheral nervous system myelin sheaths. In sheaths that contain P2 protein, it is concentrated in the area of the Schmidt-Lanterman incisures.