Scanning Electron Microscopy Shows that both Antigen Mobility and Membrane Deformation Occur in the Hemagglutination Reaction
- 1 January 1981
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 40 (1) , 1-5
- https://doi.org/10.1111/j.1423-0410.1981.tb00661.x
Abstract
A scanning electron microscopic examination of antibody-induced hemagglutination of human red blood cells by an improved enzyme-labeled antibody technique, and fixation of the reaction sequence with glutaraldehyde shows that antigen mobility and membrane deformation are necessary for the reaction to occur.This publication has 10 references indexed in Scilit:
- Conversion of incomplete antibodies to direct agglutinins by mild reduction: evidence for segmental flexibility within the Fc fragment of immunoglobulin G.Proceedings of the National Academy of Sciences, 1977
- The role of antigen mobility in anti-Rh0(D)-induced agglutination.Journal of Clinical Investigation, 1975
- Distribution and Mobility of the A, D and c Antigens on Human Red Cell Membranes: Studies with a Gold‐labelled Antiglobulin ReagentBritish Journal of Haematology, 1975
- The Role of Enzymes and Albumen in Haemagglutination Reactions: A Serological und Ulrrastrucrural Study with Ferritin-Labelled Anti-DVox Sanguinis, 1974
- Crossed immunoelectrophoresis of human erythrocyte membrane proteinsBiochimica et Biophysica Acta (BBA) - Protein Structure, 1974
- Anionic sites on the membrane intercalated particles of human erythrocyte ghost membranes. Freeze-etch localizationExperimental Cell Research, 1973
- Mechanism of Red Cell Agglutination by IgG AntibodiesVox Sanguinis, 1973
- The Fluid Mosaic Model of the Structure of Cell MembranesScience, 1972
- Quantitative Two-Dimensional Ultrastructural Distribution of Rh o (D) Antigenic Sites on Human Erythrocyte Membranes *Proceedings of the National Academy of Sciences, 1971
- The significance of erythrocyte antigen site densityJournal of Clinical Investigation, 1970