Occurrence of γ-trace in the calcitonin-producing C-cells of simian thyroid gland and human medullary thyroid carcinoma
- 1 September 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 104 (1) , 69-76
- https://doi.org/10.1530/acta.0.1040069
Abstract
.gamma.-Trace, a microprotein occurring in neuroendocrine cells, was demonstrated by immunohistochemical technique to be present in the calcitonin-producing C-cells of normal simian thyroid gland and of human medullary thyroid carcinoma. A comparatively high concentration of .gamma.-trace was demonstrated in tissue extract of neoplastic C-cells. The immunoreactive protein found in the extract had a MW and electrophoretic mobility characteristic for .gamma.-trace.Keywords
This publication has 6 references indexed in Scilit:
- Post-gamma globulin: Tissue distribution and physicochemical characteristics of dog post-gamma globulinClinica Chimica Acta; International Journal of Clinical Chemistry, 1982
- A simple two-step procedure for the purification of plasma C1q from different animal speciesImmunology Letters, 1981
- Parafollicular cells of rabbit thyroid store both calcitonin and somatostatin and resemble gut D cells ultrastructurallyHistochemistry and Cell Biology, 1979
- Quantitation of γ-trace in human biological fluids: Indications for production in the central nervous systemScandinavian Journal of Clinical and Laboratory Investigation, 1979
- A heated biuret-Folin protein assay which gives equal absorbance with different proteinsAnalytical Biochemistry, 1977
- WHISKY: A NEW PROVOCATIVE TEST FOR CALCITONIN SECRETIONActa Endocrinologica, 1976