Effect of crculatory occlusion on time to muscular fatigue.

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Abstract
Eight young adult male subjects held 25% of a maximum voluntary isometric contraction of the right biceps to fatigue. Four conditions were studied control, with no occlusion of the circulation; proximal occlusion (1-in pneumatic circumferential cuff inflated to 300 mm Hg) at the right axillary fold; distal occlusion of the right active forearm; and distal occlusion of the left inactive forearm. The subjects held the control contraction longest (mean of 293 sec). Proximal occlusion was held the shortest (135 sec). The right (215 sec.) and left (239 sec.) occlusions were held longer than the proximal occlusion but shorter than the unoccluded control. Upon repetition of conditions, the reliability coefficient was 0.94. There was no statistical difference between times to fatigue in the 2 distal forearm occlusion groups. All other differences were significant at the 0.01 level. While occlusive restriction of blood supply to an isometrically exercising muscle enhances the onset of fatigue in that muscle, occlusion of circulation elsewhere also results in a more rapid onset of fatigue.