POROKERATOSIS OF MIBELLI IN 2 MONOZYGOTIC TWINS

  • 1 January 1981
    • journal article
    • research article
    • Vol. 108  (2) , 151-156
Abstract
Two monozygotic twins had porokeratosis Mibelli and a deep mental retardation. The exploration of this nervous component is negative. The porokeratosis in 1 twin had a calloused aspect in several sites. The demonstration of the monozygotes was made by the same repartition of 16 characters (HLA and blood groups). The boys had the same aspect and the same skin disease. The twin method is discussed. The existence of the porokeratosis of Mibelli in 2 monozygotic twins is an argument for the genetic mechanism of the disease. An autosomal dominant transmission with variations in the penetrance and the expressivity of the skin disease apparently exists.