RECOVERY FROM MUSCULAR ACTIVITY AND ITS BEARING ON THE CHEMISTRY OF CONTRACTION

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Abstract
In recovery from muscular contraction (gastrocnemius of cat in situ, with intact circulation and innervation) resynthesis of phosphocreatine is slow, and of adenosine triphosphate extremely slow. The 2 reactions are independent of each other. None of the anaerobic reactions which have been postulated to furnish the energy for contraction seems capable of doing so under steady state conditions. The evidence showing that contracting muscle utilizes oxidative reactions directly as the source of energy is discussed. Only on this basis can the findings of the steady state be accounted for.

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