Distribution of Angiotensin‐Converting Enzyme Activity in Specific Areas of the Rat Brain Stem
- 1 January 1982
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 38 (1) , 281-284
- https://doi.org/10.1111/j.1471-4159.1982.tb10883.x
Abstract
Angiotensin-converting enzyme (ACE) activity was measured by a radiochemical assay in 30 specific areas of the rat brain stem. ACE activity is unevenly distributed, with a 60-fold difference between the lowest and the highest activity. The area postrema exhibits the highest activity. The substantia nigra (pars reticulata), the locus coeruleus, the areas A1 and A2, the nuclei commissuralis, and tractus solitarii have a substantial ACE activity, whereas the lowest activity is found in the raphe nuclei and the nuclei of the reticular formation.Keywords
This publication has 31 references indexed in Scilit:
- Evidence for differential localization of angiotensin‐l converting enzyme and renin in the corpus striatum of ratActa Physiologica Scandinavica, 1980
- Reduced activity of angiotensin-converting enzyme in basal ganglia in early onset schizophreniaPsychological Medicine, 1980
- Co-identity of brain angiotensin converting enzyme with a membrane bound dipeptidyl carboxypeptidase inactivating Met-enkephalinBiochemical and Biophysical Research Communications, 1979
- Inhibition of brain angiotensin‐1 converting enzyme by Bothrops jararaca nonapeptide (SQ 20881) and a prolyl analog (SQ 14225)Journal of Neurochemistry, 1978
- Huntington's chorea: Selective depletion of activity of angiotensin converting enzyme in the corpus striatumAnnals of Neurology, 1977
- Distribution of angiotensin II receptors in rat brainBrain Research, 1977
- Immunohistochemical evidence for the existence of angiotensin II-containing nerve terminals in the brain and spinal cord in the ratNeuroscience Letters, 1976
- DISTRIBUTION AND PROPERTIES OF ANGIOTENSIN CONVERTING ENZYME OF RAT BRAINJournal of Neurochemistry, 1972
- Converting enzyme content of different tissues of the ratCellular and Molecular Life Sciences, 1969