In Vitro Synergy of Caspofungin and Amphotericin B against Aspergillus and Fusarium spp
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- 1 January 2002
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 46 (1) , 245-7
- https://doi.org/10.1128/aac.46.1.245-247.2002
Abstract
We investigated the in vitro interaction of caspofungin and amphotericin B for clinical isolates of Aspergillus and FUSARIUM: Synergy tests were performed using the checkerboard method and following the NCCLS M38-P guidelines in Antibiotic Medium 3 broth supplemented to 2% glucose. Antagonism was not observed for any of the isolates tested. Caspofungin and amphotericin B were synergistic or synergistic to additive for at least half of the isolates.Keywords
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